The completed LACE trial has had a significant impact on how doctors perform gynaecological surgery in Australia and worldwide. The Laparoscopic Approach to Carcinoma of the Endometrium (LACE) trial examined the treatment of endometrial cancer via a laparoscopic (keyhole) hysterectomy versus traditional, open-abdominal surgery.
LACE involved 760 patients and 27 gynaecological cancer surgeons from 21 cancer centres across Australia and New Zealand over 15 years. The outcomes showed that women with endometrial cancer who underwent a laparoscopic hysterectomy have, an equivalent overall and disease-free survival rate compared to women who received an abdominal hysterectomy.
